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Abstract
This article reviews what is currently known about short tandem repeat (STR) allelic sequence variation in and around the twenty-four loci most commonly used throughout the world to perform forensic DNA investigations. These STR loci include D1S1656, TPOX, D2S441, D2S1338, D3S1358, FGA, CSF1PO, D5S818, SE33, D6S1043, D7S820, D8S1179, D10S1248, TH01, vWA, D12S391, D13S317, Penta E, D16S539, D18S51, D19S433, D21S11, Penta D, and D22S1045. All known reported variant alleles are compiled along with genomic information available from GenBank, dbSNP, and the 1000 Genomes Project. Supplementary files are included which provide annotated reference sequences for each STR locus, characterize genomic variation around the STR repeat region, and compare alleles present in currently available STR kit allelic ladders. Looking to the future, STR allele nomenclature options are discussed as they relate to next generation sequencing efforts underway.
Keywords
: STR Allele Sequence Variation: Current Knowledg
Future Issues
Author: Katherine Butler Gettings Rachel A. Aponte Peter M.
Vallone John M. Butler
PII: S1872-4973(15)30026-0
DOI:
Reference: FSIGEN 1368
To appear in: Forensic Science International: Genetics
Received date: 13-2-2015
Revised date: 20-5-2015
Accepted date: 10-6-2015
Please cite this article as: Katherine Butler Gettings, Rachel A.Aponte,
Peter M.Vallone, John M.Butler, STR Allele Sequence Variation: Current
Knowledge and Future Issues, Forensic Science International: Genetics
This is a PDF file of an unedited manuscript that has been accepted for publication.
As a service to our customers we are providing this early phiên bản of the manuscript.
The manuscript will undergo copyediting, typesetting, and review of the resulting proof
before it is published in its final form. Please note that during the production process
errors may be discovered which could affect the content, and all legal disclaimers that
apply to the journal pertain.
Forensic DNA; Short tandem repeat; STR loci; DNA database; Sequence variation; STR nomenclature
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Abstract
This article reviews what is currently known about short tandem repeat (STR) allelic sequence variation in and around the twenty-four loci most commonly used throughout the world to perform forensic DNA investigations. These STR loci include D1S1656, TPOX, D2S441, D2S1338, D3S1358, FGA, CSF1PO, D5S818, SE33, D6S1043, D7S820, D8S1179, D10S1248, TH01, vWA, D12S391, D13S317, Penta E, D16S539, D18S51, D19S433, D21S11, Penta D, and D22S1045. All known reported variant alleles are compiled along with genomic information available from GenBank, dbSNP, and the 1000 Genomes Project. Supplementary files are included which provide annotated reference sequences for each STR locus, characterize genomic variation around the STR repeat region, and compare alleles present in currently available STR kit allelic ladders. Looking to the future, STR allele nomenclature options are discussed as they relate to next generation sequencing efforts underway.
Keywords
: STR Allele Sequence Variation: Current Knowledg
Future Issues
Author: Katherine Butler Gettings Rachel A. Aponte Peter M.
Vallone John M. Butler
PII: S1872-4973(15)30026-0
DOI:
You must be registered for see links
Reference: FSIGEN 1368
To appear in: Forensic Science International: Genetics
Received date: 13-2-2015
Revised date: 20-5-2015
Accepted date: 10-6-2015
Please cite this article as: Katherine Butler Gettings, Rachel A.Aponte,
Peter M.Vallone, John M.Butler, STR Allele Sequence Variation: Current
Knowledge and Future Issues, Forensic Science International: Genetics
You must be registered for see links
This is a PDF file of an unedited manuscript that has been accepted for publication.
As a service to our customers we are providing this early phiên bản of the manuscript.
The manuscript will undergo copyediting, typesetting, and review of the resulting proof
before it is published in its final form. Please note that during the production process
errors may be discovered which could affect the content, and all legal disclaimers that
apply to the journal pertain.
Forensic DNA; Short tandem repeat; STR loci; DNA database; Sequence variation; STR nomenclature
Do Drive thay đổi chính sách, nên một số link cũ yêu cầu duyệt download. các bạn chỉ cần làm theo hướng dẫn.
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